Penicillinase-resistant Penicillins and Cephalosporins
نویسندگان
چکیده
منابع مشابه
Penicillinase - resistant Penicillins and Cephalosporins
The discovery of penicillinase-resistant penicillins is an important landmark in the history of antibacterial chemotherapy. Methicillin came into clinical use in 1960, and its value in the treatment of penicillin-resistant staphylococcal infection is now well established. The same is true of the isoxazolyl penicillins, oxacillin and cloxacillin, which came on to the scenes about a year later. N...
متن کاملSusceptibility of the "penicillinase-resistant" penicillins and cephalosporins to penicillinase of Staphylococcus aureus.
The activities of some semisynthetic penicillins and cephalosporins have been tested against clinical strains of Staphylococcus aureus. The apparent activity in vitro varies with the method of testing used. Determination of MICs using light inocula fails to detect the destructive effect of penicillinase on the antibiotic. This was, however, demonstrated reproducibly by the use of a technique in...
متن کاملPenicillins and cephalosporins.
Resemblances and differences between the penicillins (I) and cephalosporins (II) are considered from a chemical and biochemical point of view.
متن کاملPenicillinase-resistant Penicillins in the Treatment of Surgical Staphylococcal Infections.
although it has the advantage of being given orally, seems less effective, and ampicillin similarly. Comparative statistical evidence of the value of the various penicillins and of the antibiotics is not available, and would be difficult to obtain, but I have no personal doubt that at present in the acute infection methicillin and chloramphenical are the two most effective drugs. A major anxiet...
متن کاملOccasional Survey Choice among Penicillins and Cephalosporins *
In 1944 medical personnel in London was scattered and communications were difficult, but a meeting at the Royal Society of Medicine in November of that year was one of the most crowded ever held there. Such an audience could then have been attracted by only one subject, penicillin, which at that time was proving its worth in the treatment of battle casualties. Of the opening speakers, Fleming i...
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ژورنال
عنوان ژورنال: BMJ
سال: 1964
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5405.344